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What has Food and Drug Administration published in the Federal Register, and what is open for comment?

Food and Drug Administration published 1,915 Federal Register documents between Jan 03, 2024 and Oct 23, 2026; in 2026 so far 591 (95 final rules, 29 proposed rules, 467 notices). 56 documents from the last 120 days are still open for comment.

2026: 591 documentsOPEN FOR COMMENT: 56LAST: Oct 23, 2026

Cite: FACTANKER, https://factanker.com/federal-register/food-and-drug-administration

What stands out

Food and Drug Administration published 1,915 Federal Register documents between Jan 03, 2024 and Oct 23, 2026; in 2026 so far 591 (95 final rules, 29 proposed rules, 467 notices). 56 documents from the last 120 days are still open for comment.

Documents per year

Each year has its own page with every document.

YearDocumentsFinal rulesProposedNoticesSignificantPublication days
202659195294674156
202557674214815120
202474866306526192

Open for comment

Documents from the last 120 days whose comment period has not closed.

PublishedTypeDocumentComments closeEvidence
Aug 24, 2026NoticeProduct-Specific Guidances; Draft and Revised Draft Guidances for Industry; Availability2026-10-23record →
Sep 25, 2026RuleFood Additives Permitted for Direct Addition to Food for Human Consumption; Vitamin D2 Inactive Bakers Yeast2026-10-26record →
Aug 26, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Allegations of Regulatory Misconduct Voluntarily Submitted t2026-10-26record →
Aug 28, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Focus Groups and Interviews as Used by the Food and Drug Adm2026-10-27record →
Aug 28, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Food Canning Establishment Registration, Process Filing, and2026-10-27record →
Aug 28, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Qualitative Feedback on Agency Service Delivery2026-10-27record →
Sep 29, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Submission of Petitions: F2026-10-29record →
Aug 31, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Medical Devices; Reports of Removals and Corrections2026-10-30record →
Aug 31, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Registration of Human Drug Compounding Outsourcing Facilitie2026-10-30record →
Oct 01, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Voluntary Improvement Prog2026-11-02record →
Sep 04, 2026NoticeAdvancing Development of Botanical Drug Products; Request for Information2026-11-03record →
Aug 05, 2026NoticeEstablishment of a Quantitative Medicine Innovation Network: Scope, Feasibility, and Opportunities; Request for Information2026-11-03record →
Oct 09, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Expanded Access to Investi2026-11-09record →
Oct 09, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Biologics License Applicat2026-11-09record →
Oct 08, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Adverse Event Program for 2026-11-09record →
Sep 24, 2026NoticeImproving Patient Access to Deceased Donor Islet Cells and Cell Products; Request for Information2026-11-09record →
Sep 09, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Pregnancy Exposure Registry Enrollment Project: A Survey of 2026-11-09record →
Sep 09, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Human Cells, Tissues, and Cellular and Tissue-Based Products2026-11-09record →
Sep 11, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Medical Device Tracking2026-11-10record →
Oct 14, 2026RuleFood Additives Permitted in Feed and Drinking Water of Animals; Chromium Propionate2026-11-13record →
Oct 14, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Infant Formula Requirement2026-11-13record →
Oct 14, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Voluntary National Retail 2026-11-13record →
Oct 14, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Requirements for Cosmetic 2026-11-13record →
Sep 15, 2026NoticeStatistical Considerations for the Design of Rare Disease Clinical Investigations; Establishment of a Public Docket; Request for Information2026-11-13record →
Sep 18, 2026NoticeTarget Animal Safety Evaluation for Veterinary Monoclonal Antibody Products; Draft Guidance for Industry; Availability2026-11-17record →
Sep 18, 2026NoticeBiosimilar User Fee Act III Future Needs in the Development of Interchangeable Products Post-Workshop; Draft Strategy Document2026-11-17record →
Sep 18, 2026NoticeElectronic Submission Template for Medical Device Premarket Approval Applications (PMAs); Draft Guidance for Industry and Food and Drug Admi2026-11-17record →
Aug 20, 2026NoticePotency Assessment of Active Immunotherapy Products; Draft Guidance for Industry; Availability2026-11-18record →
Oct 06, 2026NoticeDesign and Safety Considerations for Clinical Trials Involving Ibogaine Drug Products; Request for Information2026-11-20record →
Sep 21, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Prior Notice of Imported Food Under the Public Health Securi2026-11-20record →
Sep 21, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; State Petitions for Exemption From Preemption2026-11-20record →
Sep 21, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Temporary Marketing Permit Applications2026-11-20record →
Oct 23, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Accreditation Scheme for C2026-11-23record →
Oct 09, 2026Proposed RuleRequirements for Additional Traceability Records for Certain Foods: Enforcement Policy for Certain Retail Food Establishments and Restaurant2026-11-23record →
Sep 25, 2026NoticeRobotically-Assisted Surgical Devices-Premarket Submissions; Draft Guidance for Industry and Food and Drug Administration Staff; Availabilit2026-11-24record →
Sep 25, 2026NoticeReauthorization of the Biosimilar User Fee Act; Public Meeting; Request for Comments2026-11-25record →
Aug 28, 2026NoticeCompounding Animal Drugs From Bulk Drug Substances: Compounding Under CGMP in Federally-Registered Facilities; Draft Guidance for Industry; 2026-11-27record →
Sep 29, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Protection of Human Subjects and Institutional Review Boards2026-11-30record →
Sep 02, 2026NoticePharmacokinetics in Patients With Impaired Hepatic Function: Study Design, Data Analysis, and Impact on Dosage; Draft Guidance for Industry;2026-12-01record →
Oct 09, 2026NoticeChallenges and Solutions in Lot-Level Food Traceability; Public Meeting2026-12-06record →
Oct 08, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Channels of Trade Policy for Commodities With Residues of Pe2026-12-07record →
Sep 22, 2026Proposed RuleNonclinical Testing Terminology2026-12-07record →
Sep 22, 2026RuleNonclinical Testing Terminology2026-12-07record →
Oct 09, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; MONOFERRIC2026-12-08record →
Aug 11, 2026Proposed RuleSubstances Generally Recognized as Safe2026-12-09record →
Oct 16, 2026NoticeFit-for-Purpose Rare Disease Framework Initiative; Public Meeting; Request for Information and Comments2026-12-11record →
Oct 23, 2026Proposed RuleAction Levels for Cadmium in Processed Food Intended for Babies and Young Children; Draft Guidance for Industry; Availability2026-12-22record →
Oct 23, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Product Jurisdiction and Combination Products2026-12-22record →
Oct 23, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Export Certificates for FDA Regulated Products2026-12-22record →
Jun 29, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; VYALEV2026-12-28record →
Oct 23, 2026Proposed RuleHazard Analysis and Risk-Based Preventive Controls for Human Food; Draft Guidance for Industry; Availability2027-01-21record →
Aug 10, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; DAYVIGO2027-02-08record →
Aug 10, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; BRINSUPRI2027-02-08record →
Sep 09, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; ANKTIVA2027-03-08record →
Sep 09, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; ANZUPGO2027-03-08record →
Sep 09, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; ANDEMBRY2027-03-08record →

Latest documents

PublishedTypeDocumentEvidence
Oct 23, 2026Proposed RuleHazard Analysis and Risk-Based Preventive Controls for Human Food; Draft Guidance for Industry; Availabilityrecord →
Oct 23, 2026Proposed RuleAction Levels for Cadmium in Processed Food Intended for Babies and Young Children; Draft Guidance for Industry; Availabilityrecord →
Oct 23, 2026NoticeQuestions and Answers Regarding Mandatory Cosmetics Recalls; Guidance for Industry; Availabilityrecord →
Oct 23, 2026NoticeDetermination of Regulatory Review Period for Purposes of Patent Extension; Correction of Notices-ANDEMBRY; ANZUPGO; ANKTIVA; BIZENGRI; BRINrecord →
Oct 23, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Accreditation Scheme for Crecord →
Oct 23, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Product Jurisdiction and Combination Productsrecord →
Oct 23, 2026NoticeAgency Information Collection Activities; Proposed Collection; Comment Request; Export Certificates for FDA Regulated Productsrecord →
Oct 21, 2026NoticeRegulatory Considerations for Prescription Drug Use-Related Software; Guidance for Industry; Availabilityrecord →
Oct 20, 2026NoticeNew Dietary Ingredient (NDI) Notifications and Related Issues; Identity and Safety Information About the NDI: Guidance for Industry; Availabrecord →
Oct 16, 2026NoticeFit-for-Purpose Rare Disease Framework Initiative; Public Meeting; Request for Information and Commentsrecord →
Oct 16, 2026NoticeElectronic Common Technical Document; Data Standards; Center for Drug Evaluation and Research and Center for Biologics Evaluation and Researrecord →
Oct 16, 2026NoticeElectronic Common Technical Document (eCTD); Data Standards; Supporting Forward Compatibility for eCTD 4.0record →
Oct 15, 2026NoticeRequest for Nominations for Voting Members on a Public Advisory Committee; Tobacco Products Scientific Advisory Committee (TPSAC)record →
Oct 15, 2026NoticeAuthorization of Emergency Use for Four Animal Drugs for the Prevention and Treatment of New World Screwworm; Availabilityrecord →
Oct 14, 2026RuleFood Additives Permitted in Feed and Drinking Water of Animals; Chromium Propionaterecord →
Oct 14, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Infant Formula Requirementrecord →
Oct 14, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Voluntary National Retail record →
Oct 14, 2026NoticeAdvisory Committee; Cellular, Tissue, and Gene Therapies Advisory Committee; Renewalrecord →
Oct 14, 2026NoticeAgency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Requirements for Cosmetic record →
Oct 13, 2026NoticePostapproval Manufacturing Changes to Biosimilar and Interchangeable Biosimilar Products: Questions and Answers; Guidance for Industry; Avairecord →
Oct 13, 2026RuleUse of Salt Substitutes To Reduce the Sodium Content in Standardized Foodsrecord →
Oct 09, 2026NoticeChallenges and Solutions in Lot-Level Food Traceability; Public Meetingrecord →
Oct 09, 2026Proposed RuleRequirements for Additional Traceability Records for Certain Foods: Enforcement Policy for Certain Retail Food Establishments and Restaurantrecord →
Oct 09, 2026RuleMedical Devices; Immunology and Microbiology Devices; Classification of the Hematopoietic Cell Enrichment Kitrecord →
Oct 09, 2026RuleMedical Devices; Cardiovascular Devices; Classification of the Infant Pulse Rate and Oxygen Saturation Monitor for Over-the-Counter Userecord →
Oct 09, 2026RuleMedical Devices; Immunology and Microbiology Devices; Classification of the System for Detection of Nucleic Acid From Non-Viral Microorganisrecord →
Oct 09, 2026NoticeElite Laboratories, Inc. et al.; Withdrawal of Approval of 16 Abbreviated New Drug Applications; Correctionrecord →
Oct 09, 2026NoticeAmneal Pharmaceuticals of New York, LLC; Withdrawal of Approval of Abbreviated New Drug Application for Celecoxib Capsules, 50 Milligrams, 1record →
Oct 09, 2026NoticePar Health USA LLC, U.S. Agent for PH Health Limited, et al.; Withdrawal of Approval of 37 Abbreviated New Drug Applicationsrecord →
Oct 09, 2026NoticeDetermination That LASIX (Furosemide) Oral Solution, 10 Milligrams/Milliliter, Was Not Withdrawn From Sale for Reasons of Safety or Effectivrecord →

Method

Source: the Federal Register API (Office of the Federal Register, National Archives), every document since January 2024 with its type, agencies, publication date, effective date, comment deadline, dockets and CFR parts. One record per agency and publication day holds that day's documents; a document listed under two agencies counts for both, as the Register itself lists it. Counts are of documents, not pages. Links go to the official document on federalregister.gov. Updated daily after publication.

Entity record →All agencies and method →

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